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Biologique Recherche and I agree completely on the importance of customization. No two skins are alike, and their conditions can change daily depending on many factors including climate, diet, health, age, and lifestyle. Skin Serums are a vital step in our daily skincare routines. They contain the most potent form of active ingredients with the lowest molecular weights, so that they can penetrate the skin more easily and are ale to treat specific skin conditions 

The Biologique Recherche Quintessential Serums are the purest formulations in the  Biologique Recherche  range. They are designed to treat a variety of skin imbalances including dehydration, excess sebum, fine lines, elasticity, and devitalized skin, while penetrating the epidermis rapidly and efficiently, creating outstanding and powerful results. They are water-based and the main active ingredients are amino acids or short peptides and a bare minimum of preservatives. 

Below is a breakdown of some of my favorites:

Serum A-Glyca

This Ultra-Pure Quintessential Serum is designed to block glycation. Glycation is the breakdown of collagen and elastin in the skin as a reaction to excess sugar in the body. Serum A-Glyca works like a magnet to the extra sugars. Undigested sugars can cause fragility of collagen which results in fine lines and wrinkles. Two months of continued use of this serum can reverse up to two years of glycation.  

Serum A-Glyca Benefits Include: 

  • Acts against the phenomenon of glycation 
  • Protects proteins within the skin’s structure 
  • Reduces seep lines and wrinkles 
  • Reduces signs of tiredness on the face 
  • Contributes to the skin’s firmness 
  • Brings radiance to the complexion 

How to Use 

Take a few drops of the Serum A-Glyca. Onto clean skin, apply the serum morning and night over the entire face, neck and décolleté using gentle ascending movements until the complete absorption of the product.  

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Sérum Collagène Natif 

Sérum Collagène Natif is an intense treatment to restore and improve volume, tone strength and plumpness. It is recommended for dehydrated skin and specifically formulated with biological collagen extracts. The skin will be left hydrated, silky soft and glowing. From the very first application, the face is plumped up, more supple and comfortable. 

Sérum Collagène NatifBenefits Include: 

  • Tones and tightens the skin 
  • Tightens pores 
  • Redefines the oval of the face 
  • Replenishes the skin’s moisture content 
  • Hydrates the upper layers of the epidermis 
  • Binds water and restores the barrier function of the epidermis 

How to Use 

Apply 0.5ml (10 drops) of Serum Collagène Natif on clean skin over the whole face, neck, and cleavage in a light ascending massage until the product has been completely absorbed. Serum Collagène Natif can be combined with all the other biological Quintessential Serums. 

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Serum Colostrum VG

Serum Colostrum VG is intended for severely dry, or damaged skin. With intense moisturizing properties, this serum is a savior for damaged skin. Its formula provides the water and fat required to restore the water content of the epidermis by hydrating and reconstructing the damaged protective lipid film. Colostrum extracts help to prevent future drying, and repair dehydrated skin. This serum is intended for use after exposure to sun or harsh conditions, restoring comfort and plumpness to the skin.   

Serum Colostrum VG Benefits Include: 

  • Intensely restores lipids in the skin 
  • Maintains in-depth skin hydration 
  • Strengthens skin barrier 
  • Prevents tightness 
  • Provides a sensation of comfort and suppleness 

How to Use: 

To apply, put 0.5 ml (10 drops) on the face, skin and cleavage and allow time to absorb. Serum Colostrum can be combined with all other Quintessential Serums.  

Serum Complexe Iribiol

For those who struggle with acne prone and oily skin, the Serum Complexe Iribiol is the answer. The combination of salicylic and zinc helps to clean the skin while simultaneously healing the epidermis. Salicylic acid works to clear out dead skin and excess oil from your pores, targeting the acne causing buildup. Complexe Iribiol can be used on congested areas of the skin with excess oil to treat acne and imperfections.  

Serum Complexe Iribiol Benefits Include: 

  • Regulates sebaceous secretions 
  • Tightens pores 
  • Prevents, slows down and corrects the formation of skin imperfections  
  • Stimulates cell renewal and promotes healing of skin imperfections 

How to Use: 

To use, apply 0.5 ml (10 drops) onto the face, neck, and cleavage, focusing on the T-Zone. Leave the product until it is fully absorbed into the skin.  

Serum Dermopore

Serum Dermopore is a rebalancing serum that is good for skin with oily conditions. Containing java tea, it works to reduce sebum secretion, tighten pores, refine skin irregularities, and purify the epidermis. Pores play a vital role in the physiology of the skin, allowing it to “breathe,” but it is essential to prevent and treat dilated pores before inflammation sets in and acne appears. This serum is, therefore, a care product for daily prevention for seborrheic skin types, which are prone to acne and skin imperfections. Your skin will be left perfectly matte, more balanced, and even. 

Serum Dermopore Benefits Include: 

  • Evens out the complexion 
  • Tightens dilated pores 
  • Prevents pore dilation and comedones formation 
  • Refines skin texture irregularities 
  • Regulates the secretion of sebum 

How to Use: 

Extract 1 ml (20 drops) of Serum Dermopore. On clean skin, apply the serum to the whole face, neck and décolleté by lightly massaging upwards until complete absorption of the product. Apply well on the median zone which is denser in sebaceous glands. 

Serum Extraits Tissulaires

Early signs of dehydration in the skin can be stopped with the Serum Extraits Tissulaires, which contains cellular oligopeptides. These peptides work to moisturize the upper layers of the skin, where the first signs of drying appear. Its core formula continuously captures and diffuses water to reestablish the skin’s water balance. This serum works to hydrate and strengthen the skin and is suitable for all skin conditions. It can be combined with other Quintessential Serums.  

Serum Extraits Tissulaires Benefits Include: 

  • Moisturizes the upper layers of the epidermis 
  • Helps maintain good hydration daily 
  • Improves the skin’s barrier function 
  • Improves the skin’s quality 
  • Provides a sensation of comfort and softness 

How To Use: 

Apply 0.5 ml (10 drops) to clean skin on the face and neck, allowing time to absorb.  

Serum Iso-Placenta


An anti-acne trace corrective care product, the Iso-Placenta serum improves skin restoration to smooth the cutaneous microrelief while reducing redness and marks. Containing placental bio stimulant protein extracts, it works to strengthen and rebuild the epidermis. With healing, strengthening, and restorative properties, this serum is great for those with acne scarring.  

Serum Iso-Placenta Benefits Include: 

  • Corrects acne traces 
  • Regulates the synthesis of growth factors to support the growth, differentiation, and migration of cells 
  • Regenerates and improves skin restoration 
  • Smooths the skin’s microrelief 
  • Reduces redness and marks 
  • Reduces blemishes and conceals spots 

How To Use: 

To use, apply 0.5 ml (10 drops) to the face and neck, or directly to imperfections. The intensive treatment is effective enough for targeted spot treatment. 


Serum VG Tensil

Serum VG Tensil is an advanced, intensive treatment intended to give the skin an overall boost. It is recommended for dull or sagging skin conditions. The formula contains plant extracts of rye and hazelnut oligopeptides, which help to firm and tone the muscles supporting the skin. It was formulated to regenerate the skin’s fibrous network which supports its structure. This intense serum is formulated for regular use or special events where you want to look your best.  

Serum VG Tensil Benefits: 

  • Firms and tones the tissue supporting the skin 
  • Contributes to cellular renewal by stimulating fibroblasts and keratinocytes 
  • Contributes to restore the fibrous network 
  • Boosts collagen synthesis 
  • Smooths fine lines and wrinkles 

How to Use: 

Apply 10 ml (20 drops) to perfectly clean skin, allowing it time to absorb. Apply to the whole face, neck, and cleavage by gently smoothing in an upwards motion until the product has been completely absorbed.